Not an expert on baritones or bass runs, but am I correct to assume that it will only really work for some chord changes - also meaning that to use them, you would need to focus on playing songs in just a few keys?
My experience on the topic is from linear tuned Tenor ukuleles.
While I havent yet incorporated bass runs, for arpeggios I have tried to put the root as the lowest note, and for other stuff I have tried to alter between bass notes and strumming.
I find that for the notes to be bass like compared to the strumming, there is less that an octave available. And if you push it to an octave, the order of the notes is not necessarily ideal for runs. Playing F as a bass note on a tenor is not good.
I would focus on finding the keys that work well for bass lines with the range of your instrument. If you mostly use the I, IV and V chords in the runs, it should be straight forward to find the strong keys.